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Methyldibromo glutaronitrile (MDBGN) is a widely used preservative. It is made by reacting bromine with 2-methyleneglutaronitrile below 30 °C. An allergy to the chemical can be discovered by performing a patch test. ==History and allergy== In the mid-1980s, a maximum concentration of 0.1% in stay-on and rinse-off cosmetics was allowed. It was discovered soon afterwards that it caused allergic contact dermatitis to people with eczema.〔 It has been in use since the 1990s as a preservative in skin care products such as lotions, wet wipes, shampoo, and liquid soaps. Industrial applications include its use in preserving oils, glues, and medical gels. In 2005, the EU banned its use in stay-on products, and in 2007 banned it in rinse-off products.〔 In 2005–06, methyldibromoglutaronitrile/ phenoxyethanol was the ninth-most-prevalent allergen in patch tests]] (5.8%).〔Zug KA, Warshaw EM, Fowler JF Jr, Maibach HI, Belsito DL, Pratt MD, Sasseville D, Storrs FJ, Taylor JS, Mathias CG, Deleo VA, Rietschel RL, Marks J. Patch-test results of the North American Contact Dermatitis Group 2005–2006. Dermatitis. 2009 May–Jun;20(3):149-60.〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Methyldibromo glutaronitrile」の詳細全文を読む スポンサード リンク
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